One of a number of initiatives, the pairing will see both companies work in tandem to educate families on the importance of digital wellbeing, online safety and peer pressure.
TikTok already offers a variety of in-app tools such as the ability to disable or restrict comments and an option to report inappropriate content to enable users to self-police.
However, the app has come under fire in recent months having been hit with a $5.7m fine over 'disturbing' child privacy failings.
Then, in February the National Society for the Prevention of Cruelty to Children (NSPCC) called it out for failing to protect kids.
"We know that a significant amount of children are being contacted via popular livestreaming apps, such as TikTok, by abusers who are using them as a hunting ground," the charity warned.
Patrick Nommensen, global public policy, at TikTok said it was "excited to join Internet Matters in this industry collaboration."
He added: "Promoting a safe and positive experience is TikTok’s top priority since the very beginning and we will continue to raise awareness around important issues including online safety and digital wellbeing."
Carolyn Bunting, chief executive of Internet Matters added: “Parents regularly tell us they feel their child has a superior knowledge of the latest apps and new technologies. They want to know more about what positive steps they can take to keep their children safe in the digital world.
“Working in partnership with TikTok can ensure that we provide the very best advice and support for families when they need it most.”
The pairing follows other recent initiatives spearheaded by TikTok such as Safer Internet Day which drew 1.6 million participants from 14 countries.