The agency told The Drum that Duan Evans, international executive creative director, would continue to lead the London studio with the help of executive creative director Masaya Nakade.
Managing director Sam Kelly said: “We'd like to thank Wayne for his dedication and commitment during his time at AKQA. I’ve personally enjoyed working with him and wish him all the best for the future.
"We won’t be looking to replace him immediately as we already have a significant and exceptionally talented creative team.”
Deakin joined AKQA on a freelance basis in 2015 before coming aboard permanently. In the last five years he has held prominent positions at AKQA, Doner and Engine and before that he carved out his reputation as a creative director with the likes of Jam and Jung von Matt.
Deakin said: "I've enjoyed my time with AKQA and very proud of helping make it the UK's most awarded digital agency.
"It was time for a new adventure and [I'm] looking forward to exploring opportunities in the agency world or maybe in a different creative offering."